Janice Newell Bissex

 

Helpful Resources

​​​

• ProjectCBD.org

• Leafly.com

• SafeAccessNow.org

• CannabinoidMedicines.org

• Herb.co

• UnitedPatientsGroup.com

• WeedMaps.com/learn

• Cannaconnection.com

• Ellementa.com

• HolisticCannabisAcademy.com - Contact Janice for a discount on this training program

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Research Studies

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Addiction

​

• CBD protects against alcohol-induced brain damage:

  • ​https://norml.org/news/2005/05/26/pot-compound-protects-against-alcohol-induced-brain-damage

​

• CBD reduces cravings and anxiety during heroin/opioid withdrawal: 

  • ​https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2019.18101191

  • https://www.cnn.com/2019/05/21/health/heroin-opioid-addiction-cbd-study/index.html

​

• Addiction

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285050/

  • https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.13724

 

ADD/ADHD

​

• Cannabis and ADD/ADHD: 

  • ​https://www.projectcbd.org/medicine/cannabis-adhd-emerging-therapeutic-option

  • https://www.leafly.com/news/health/cannabis-and-addadhd

​

• Current research overview: 

  • https://www.projectcbd.org/addadhd

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• CBD improves social interaction and hyperactivity in rats:

  • https://www.ncbi.nlm.nih.gov/pubmed/22495620

​

• Improvement in cognition and behavior in ADHD with using cannabinoid medication: 

  • https://www.europeanneuropsychopharmacology.com/article/S0924-977X(16)30912-9/pdf

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Alzheimer's Disease

​​

• Summary of articles on CBD and cannabis in the treatment of Alzheimer's: 

  • ​https://www.projectcbd.org/alzheimers-disease

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• CBD prevents social recognition memory deficits in mice with Alzheimer's:

  • ​https://content.iospress.com/articles/journal-of-alzheimers-disease/jad140921

​

• CBD and cannabis for Alzheimer's disease:​​

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970569/
  • ​https://sanfrancisco.cbslocal.com/2017/11/03/alzheimers-disease-medical-marijuana/

​

Amyotrophic lateral sclerosis (ALS/Lou Gehrig Disease)

​

• Cannabis and ALS:

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270417/

​

• ​Neurological aspects of CBD:​

  • ​https://www.ncbi.nlm.nih.gov/pubmed/28412918

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• Cannabis and ALS:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/20439484

​

• ALS News Today article:

  • ​https://alsnewstoday.com/2017/02/28/can-cannabinoids-be-a-potential-therapeutic-tool-in-amyotrophic-lateral-sclerosis/

 

Anxiety, Depression​, and Mental Health

​

• Leafly article & Abstract of research study – regular cannabis users have a blunted stress response, could suggest cannabis is useful for anxiety:

  • https://www.leafly.com/news/health/could-cannabis-eventually-replace-anti-anxiety-medications, https://link.springer.com/article/10.1007%2Fs00213-017-4648-z

​

• CBD for panic attacks:

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412699/ 

​​

• CBD helps to decrease anxiety and depression:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/24923339

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161644/

​

• CBD oil for anxiety:

  • ​https://greencamp.com/cbd-for-anxiety/

  • https://www.medicalnewstoday.com/articles/how-to-use-cbd-for-anxiety#how-to-use

  • https://cannabishealthnews.co.uk/2021/01/28/research-shows-cbd-has-positive-impact-on-anxiety-and-stress/

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648779/

  • https://www.projectcbd.org/condition/10

​

• How CBD can help with mood disorders:

  • ​https://www.hellomd.com/health-wellness/5c392b7bf07c6f0009ab3145/how-cbd-can-help-with-mood-disorders

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• CBD and SSRIs:

  • ​https://www.hellomd.com/answers/57c8e1f36f4f600007e0ca69/is-it-safe-to-take-cbd-oil-and-ssri-at-the-same-time

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• Anxiety Relief without the High:

  • ​https://www.npr.org/sections/health-shots/2018/04/23/604307015/anxiety-relief-without-the-high-new-studies-on-cbd-a-cannabis-extract

​

• NIH Report: Effectiveness of CBD Oil for Pediatric Anxiety and Insomnia:

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101100/

​

• Medical News Today, Can CBD Oil Help Anxiety?:

  • ​https://www.medicalnewstoday.com/articles/319622.php

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• Forbes: Can CBD replace antidepressants?

  • ​https://www.forbes.com/sites/sarabrittanysomerset/2018/08/27/can-cbd-replace-antidepressants/#39d4316c4d3d

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• CBD and Depression

  • ​https://www.hellomd.com/health-wellness/5c17fd6b33f74d0008bd994d/how-cbd-can-relieve-symptoms-of-depression

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• CBD may offer fast-acting antidepressant action:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/26711860

​

• Study shows CBD decreased anxiety 80% and improved sleep 67%:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/30624194

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• Antipsychotic properties of CBD in humans:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/25667194 

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• Best and worst cannabis strains for anxiety:

  • ​https://www.leafly.com/news/science-tech/got-anxiety-study-finds-cannabis-strains-to-try-or-avoid

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• Cannabis for anxiety and stress:

  • ​https://www.happyvalley.org/resources/cannabis-stress-anxiety/

  • https://www.frontiersin.org/articles/10.3389/fpsyt.2021.729800/full

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• Facts and Statistics on anxiety and depression:

  • https://adaa.org/about-adaa/press-room/facts-statistics

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• Cannabis and anorexia:

  • ​https://www.eatingdisorderhope.com/blog/marijuana-eating-disorder-sufferershttps://hightimes.com/health/cannabis-mental-health-anorexia-nervosa/

  • https://www.cmcr.ucsd.edu/index.php/background/studies/active-studies/228-gray-anorexia-nervosa

  • https://cannabis.net/blog/how-to/can-cannabis-help-treat-eating-disorders

  • https://www.psychologytoday.com/us/blog/your-brain-food/201204/the-connection-between-anorexia-bulimia-and-marijuana

​​​

Arthritis

​

• Published research – abstract only – cannabis may help with the pain and inflammation from arthritis:

  • http://onlinelibrary.wiley.com/doi/10.1111/1756-185X.13146/abstract

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• CBD for rheumatoid arthritis:

  • ​https://drive.google.com/file/d/1c70oWRLIiYWItIl2Y7EzDn-_9jyvBvfV/view

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• Leafly on cannabis and arthritis:

  • https://www.leafly.com/news/health/cannabis-and-arthritis

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• CBD reduces inflammation and pain in rats:

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851925/

​

• Studies on CBD and arthritis:

  • https://www.projectcbd.org/arthritis

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• CBD oil: should you try it for arthritis?

  • https://www.arthritis.org/living-with-arthritis/treatments/natural/supplements-herbs/cannabidiol-oil.php​

​

• CBD oil for arthritis symptoms:

  • https://creakyjoints.org/alternative-medicine/cbd-oil-for-arthritis-pain/

​

Autism

​

• Study in Israel shows 80% of children with autism showed improvement with CBD:

  • ​https://www.leafly.com/news/health/research-cbd-autism-therapy-promising-results

​

• How CBD may help children with autism:

  • ​https://herb.co/marijuana/news/cbd-and-autism-complete-guide

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• CBD suggested as candidate for treatment of ASD:

  • ​​https://www.ncbi.nlm.nih.gov/pubmed/30171992

  •  https://www.projectcbd.org/book-excerpt-autism-and-endocannabinoid-dysfunction

​

• Cannabis and CBD for Autism:

  • ​https://norml.org/news/2021/06/03/review-data-is-promising-regarding-use-of-cannabinoids-for-autism

  • https://www.leafly.com/news/health/cannabis-cbd-autism-treatment

​

• Israeli study showed improvement in behavior, decrease in anxiety with high CBD cannabis:

  • ​https://n.neurology.org/content/90/15_Supplement/P3.318

​

• USA Today article on the use of marijuana to treat autism:

  • ​https://www.usatoday.com/story/news/world/2017/04/25/marijuana-pot-treatment-children-autism-cannabis-oil/100381156/

​

• Real life examples of CBD use in children with autism:

  • http://www.newsweek.com/2018/02/23/really-good-weed-why-cannabis-may-be-worlds-most-effective-remedy-core-806758.html

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• Children with lower anandamide levels more likely to have autism:

  • ​https://molecularautism.biomedcentral.com/articles/10.1186/s13229-018-0203-y

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• Autism and CBD oil:

  • ​​https://basresearch.com/science/autism-and-cbd-oil/

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• New 2019 study to look at the effects of CBD on autism:

  • ​https://www.greenentrepreneur.com/article/312723

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Bone health

​

• CBD protects against osteoporosis via CB1 receptors:

  • https://www.ncbi.nlm.nih.gov/pubmed/19656492

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001217/

​

• Summary of studies on cannabis and CBD for bone health:

  • https://www.projectcbd.org/osteoporosisbone-health

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• CBD improves healing of bone fractures:

  • ​https://www.sciencedaily.com/releases/2015/07/150716124359.htm

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• CBD enhances fracture healing:

  • ​https://onlinelibrary.wiley.com/doi/full/10.1002/jbmr.2513

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• CBD boosts bone healing:​

  • https://www.medicalnewstoday.com/articles/297012.php

  • https://pubmed.ncbi.nlm.nih.gov/25801536/ 

​

Cancer and chemotherapy side effects

​

• Cannabinoids & Cancer

  • ​https://www.projectcbd.org/medicine/cannabinoids-cancer-clinic

​

• Research on Cannabis and Cancer:

  • ​https://www.analyticalcannabis.com/articles/cannabis-and-cancer-what-does-the-research-say-312608

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• CBD for nausea:

  • ​https://www.projectcbd.org/medicine/managing-nausea-cannabis

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• Cannabis for breast cancer:

  • ​https://www.e-digitaleditions.com/i/1426211-cannabis-patient-care-november-issue/11

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• American Association for Cancer Research article:

  • http://cancerres.aacrjournals.org/content/68/2/339.full​

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• Cannabis use during immunotherapy may be contraindicated:

  • ​https://drive.google.com/file/d/1cLRrC5SFyyCp7qR2bozA3AMPuHy0PFph/view

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• CBD may promote gastric cancer/lung cancer cell death:

  • ​https://www.nature.com/articles/s41419-019-2001-7

  • https://www.mdpi.com/1424-8247/14/11/1169 

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• Cannabis cuts tumor growth:

  • ​http://globalhealthtimes.com/2019/03/08/harvard-university-finds-cannabis-cuts-tumor-growth-in-half-in-three-weeks/

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• A guide to cannabis and cancer:

  • ​https://www.marijuanadoctors.com/blog/cannabis-resources-for-cancer/

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• Cannabis and cancer:

  • https://www.marijuanadoctors.com/conditions/cancer/

  • https://www.rxleaf.com/one-more-way-thc-fights-breast-cancer/

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• A Patient's Guide to Using Cannabis for Cancer:

  • ​​https://www.leafly.com/news/health/how-to-use-medical-marijuana-for-cancer?

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• Cannabis efficacy in the treatment of cancer-related pain:

  • ​https://drive.google.com/file/d/1n36K2tV2ZHGlOcPQG-iChLrqX1kJd8Ch/view

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• Cannabinoids in cancer treatments:

  • http://cancerres.aacrjournals.org/content/68/2/339

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• NIH Research on Cannabis and Cancer:

  • ​https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq

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• CBD inhibition of colon carcinogenesis

  • ​https://www.ncbi.nlm.nih.gov/pubmed/24373545

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• Cannabis and Cancer

  • ​https://green-flower.com/episodes/953/cannabis-and-cancer

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• Cannabis and Colon Cancer

  • ​https://unitedpatientsgroup.com/Patients-Room-colon-cancer

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• Cannabis increases survival rate in glioblastoma patients

  • ​https://www.green-flower.com/articles/918/cannabis-for-brain-cancer?

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• Cannabis and GI/colon cancer:

  • http://www.thctotalhealthcare.com/category/colon-cancer/

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• Published research – In early tests of cannabis for chemotherapy induced nausea in rats and people, cannabis is effective but should be tested further:

  • http://online.liebertpub.com/doi/pdfplus/10.1089/can.2016.0006

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• Cochrane systematic review suggest that cannabis may be helpful in treating nausea and vomiting from chemotherapy:

  • http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009464.pub2/abstract

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Cannabis/CBD 101

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• Map of cannabis legality by state:

  • ​https://disa.com/map-of-marijuana-legality-by-state

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• Historical Timeline of Cannabis Use:

  • ​https://medicalmarijuana.procon.org/historical-timeline/

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• The most impactful cannabis studies:

  • https://www.leafly.com/news/science-tech/most-impactful-marijuana-research-studies-of-all-time

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• 50 surprising benefits of cannabis:

  • ​https://news.green-flower.com/50-life-enhancing-benefits-of-cannabis/

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• Overview of the endocannabinoid system:​​

  • https://www.projectcbd.org/science/endocannabinoid-discovery-timeline

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789136/

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• In depth scientific review of cannabis therapy:

  • ​https://journals.physiology.org/doi/full/10.1152/physrev.00002.2016

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• How CBD affects the body:

  • ​https://www.leafly.com/news/cbd/what-does-cbd-do

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• Top medical uses of cannabis:

  • https://green-flower.com/articles/574/medical-uses-of-cannabis

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• Overview of cannabis as preventive medicine:

  • https://health.usnews.com/health-care/for-better/articles/2017-12-29/the-best-offense-preventive-medicine-gains-an-ally-in-cannabis

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• CBD Users Manual:

  • ​​https://www.projectcbd.org/guidance/cbd-users-manual

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• Inflammation:

  • ​https://www.projectcbd.org/inflammation

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/

  • https://medium.com/@DrFrank./cannabis-vs-anti-inflammatories-d8beb06d080f

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• Cannabis and seniors:

  • https://www.hellomd.com/health-wellness/5a9c921df24d1300077ccb78/top-5-senior-conditions-that-can-be-treated-with-cannabis

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• Cannabinoids as antioxidants:

  • ​https://www.projectcbd.org/about/book-excerpt/cannabinoids-and-oxidation

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• Published article – Panel discussion on the National Academy of Science’s recent report on cannabis. Conclusions: the National Academy found strong evidence that cannabis is effective for chronic pain, nausea and vomiting from chemotherapy, and spasticity from MS. Moderate evidence for sleep disorders caused by chronic illness:

  • http://online.liebertpub.com/doi/pdfplus/10.1089/can.2017.29009.dpi

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• Published meta-analysis from the Journal of the American Medical Association – Cannabis effective for chronic pain and spasticity, some evidence for nausea and vomiting from chemotherapy, HIV weight gain, sleep issues, and Tourette’s:

  • https://jamanetwork.com/journals/jama/fullarticle/2338251

​

• Published clinical review from JAMA – only the abstract is available. Cannabis is effective for “chronic pain, neuropathic pain, and spasticity due to multiple sclerosis”:

  • https://jamanetwork.com/journals/jama/article-abstract/2338266?redirect=true

​

• Published research – these disorders may be related to underlying deficits in the endocannabinoid system. Conclusion: research on treatment of Migraine, Fibromyalgia, and IBS is promising, and now that there’s a plausible physiological mechanism, randomized controlled trials should be conducted:

  • http://online.liebertpub.com/doi/pdfplus/10.1089/can.2016.0009

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• Published research – cross sectional survey of cannabis users and their perceptions of efficacy. Patient reported outcomes are favorable (86% say it is helpful):

  • http://online.liebertpub.com/doi/pdfplus/10.1089/can.2016.0007

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• Single compound versus whole plant CBD:

  • ​https://www.projectcbd.org/science/cannabis-pharmacology/single-compound-vs-whole-plant-cbd

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• CBD drug  interactions:

  • ​https://www.projectcbd.org/science/cannabis-pharmacology/cbd-drug-interactions-role-cytochrome-p450

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• CBD with Zoloft:

  • ​https://www.pharmacistanswers.com/questions/does-cbd-cannabidiol-interact-with-zoloft-sertraline

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• Safety profile of CBD:

  • ​https://echoconnection.org/research-confirms-cbd-favorable-safety-profile/

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• FDA says many CBD products sold online are mislabeled:

  • ​https://www.fda.gov/newsevents/publichealthfocus/ucm484109.htm

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• Only 3 of 25 CBD products contained within 20% of what is claimed on label:

  • ​https://pubmed.ncbi.nlm.nih.gov/32431186/

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• Positive drug tests using CBD:

• https://norml.org/news/2020/11/12/clinical-trial-hemp-derived-products-containing-thc-levels-below-federal-standards-trigger-positive-drug-test-results​

​

• Patent US6630507: Cannabinoids as antioxidants and neuroprotectants:

  • ​https://pubchem.ncbi.nlm.nih.gov/patent/US6630507#section=Patent-Submission-Date

  • https://uspatent6630507.com/

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• CBD and Immunity:

  • ​​https://www.projectcbd.org/science/cannabis-and-immune-system

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• CBD and liver disease:

  • https://www.projectcbd.org/science/cbd-toxic-liver

  • https://www.projectcbd.org/news/quick-hits/cbd-and-liver-damage

  • ​​https://www.projectcbd.org/news/quick-hits/cbd-treatment-liver-impairment

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• What do do if you get too high from cannabis:

  • ​https://weedmaps.com/learn/cannabis-and-your-body/how-to-sober-up-from-weed/

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• Qualifying conditions for a medical marijuana card by state:

  • ​https://www.leafly.com/news/health/qualifying-conditions-for-medical-marijuana-by-state

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Cardiovascular Disease and Stroke

​

• Cannabis use not associated with hardening of the arteries:

  • ​https://norml.org/news/2021/01/07/study-history-of-marijuana-use-not-associated-with-hardening-of-the-arteries

​

• CBD and cannabis may decrease incidence and improve stroke outcomes:

  • ​​https://www.green-flower.com/articles/611/cannabis-and-strokes

​

• CBD reduces brain damage after stroke:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/28012949

  • https://www.projectcbd.org/hub/stroke 

  • https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.023587

​

• Is the cardiovascular system a therapeutic target for cannabidiol?:

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579247/

 

Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (ME)

• CBD and cannabis may improve symptoms of chronic fatigue

  • https://www.projectcbd.org/medicine/cannabis-and-chronic-fatigue-syndrome

• Inflammatory Issues in Chronic Fatigue Syndrome

  • https://advances.sciencemag.org/content/1/1/e1400121.full​

 

Cooking with Cannabis

​

• How to make cannabis infused oil:

  • https://www.leafly.com/news/lifestyle/recipe-how-to-make-cannabis-cooking-oil

  • ​​https://www.medicaljane.com/category/cannabis-classroom/cooking-with-cannabis/#intro-to-cooking-with-cannabis

​

• Cannabutter recipe:​

  • ​https://www.leafly.com/news/lifestyle/recipe-how-to-make-basic-cannabutter

  • ​https://www.tastecooking.com/recipes/cannabutter/

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• Jeff the 420 Chef:

  • ​​https://www.jeffthe420chef.com/

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• Common mistakes cooking cannabis edibles:

  • https://www.leafly.com/news/cannabis-101/tips-for-cooking-better-cannabis-oil-cannabutter

​

​​

Concussion and Traumatic Brain Injury

 

• CBD and THC in the treatment of concussion / head injuries:

  • ​https://www.green-flower.com/articles/630/cannabis-can-help-traumatic-brain-injury​https://www.projectcbd.org/science/no-brainer-cbd-and-thc-head-injuries

  • https://www.integrativepractitioner.com/topics/news/new-thoughts-post-concussion-syndrome-treatment

  • https://www.concussionalliance.org/cbd-research

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574256/

​

• Cannabis users recover from traumatic brain injuries faster than non users:

  • ​https://www.omagdigital.com/publication/?m=60701&i=676479&p=20

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• CBD and THC prevent glutamate neurotoxicity

  • https://www.pnas.org/content/95/14/8268.full

​

Diabetes

​

• CBD for Diabetes?

  • https://www.endocrineweb.com/cbd-diabetes

​

• Effect of cannabis use on insulin resistance:

  • http://www.amjmed.com/article/S0002-9343%2813%2900200-3/abstract

​

• Diabetes and cannabis:

  • https://pubmed.ncbi.nlm.nih.gov/27573936/

  • https://pubmed.ncbi.nlm.nih.gov/34981965/

  • ​https://www.thediabetescouncil.com/diabetes-and-marijuana-a-possible-treatment/

​

• CBD and THCV in type 2 Diabetes:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/?term=27573936

​

• Cannabidiol lowers incidence of diabetes in mice:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/16698671

​

• American Journal of Medicine - cannabis use associated with lower insulin resistance:

  • ​https://www.amjmed.com/article/S0002-9343%2813%2900200-3/abstract

​

• Clinical trial on CBD and THCv effects on glycemic control:

  • ​​https://www.ncbi.nlm.nih.gov/pubmed/?term=27573936

​

• Diabetes and CBD resources:

  • ​https://www.projectcbd.org/diabetes

​

Dosing

• General dosing instructions:

  • ​https://www.jannabiswellness.com/dosing-instructions

• How to dose cannabis edibles:

  • https://www.leafly.com/news/cannabis-101/cannabis-edibles-dosage-guide-chart​

  • https://www.healthline.com/health/how-long-do-edibles-take-to-kick-in#duration

  • https://weedmaps.com/learn/products-and-how-to-consume/edibles/https://emilykylenutrition.com/edible-dosage-calculator/

 

Endocannabinoid System

• Mechanism of endocannabinoid system:

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295/

​

• Article in The Scientist Journal:

  • ​https://www.the-scientist.com/features/your-body-is-teeming-with-weed-receptors-31233

​

• The endocannabinoid system as a universal regulator:

  • ​https://www.jyi.org/2018-june/2018/6/1/the-endocannabinoid-system-our-universal-regulator

 

Epilepsy/Seizure disorders

​

• CBD and drug-resistant childhood seizure disorders:

  • https://www.scientificamerican.com/article/marijuana-treatment-reduces-severe-epileptic-seizures/

​

• Study of CBD and epilepsy reported in Epilepsy & Behavior Journal:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/25935511

​

• New England Journal of Medicine, CBD and Dravet Syndrome

  • ​https://www.nejm.org/doi/full/10.1056/NEJMoa1611618#iid=t01

​

• Low dose of CBD liquid eases epilepsy seizures:

  • https://www.webmd.com/epilepsy/news/20180516/low-dose-of-cbd-oil-eases-epilepsy-seizures#2

​

• ​​​Cannabinoids in the treatment of epilepsy:

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767492/

​

• CBD and Epilepsy:

  • ​https://pubmed.ncbi.nlm.nih.gov/31895184

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000162/

  • https://journals.lww.com/neurotodayonline/Fulltext/2019/12050/Evidence_on_CBD_Use_for_Pediatric_Epilepsy_Emerges.4.aspx

  • https://www.projectcbd.org/about/clinical-research/cbd-and-epilepsy

​

• Cannabis and severe epilepsy:

  • https://www.nbcnews.com/health/health-news/cannabis-drug-reduces-seizures-severe-epilepsy-cases-n764381

​

• Overview of CBD use in childhood seizures:

  • https://www.psychologytoday.com/us/blog/psych-unseen/201706/cannabis-kids-can-marijuana-treat-childhood-seizures ​

​

​​

Fibromyalgia and Autoimmune Disorders

​

• Leafly article on fibromyalgia:

  • https://www.leafly.com/news/health/medical-marijuana-fibromyalgia-treatment

​

• Endocannabinoid deficiency and fibromyalgia:

  • ​https://www.liebertpub.com/doi/pdfplus/10.1089/can.2016.0009

​

• CBD and fibromyalgia:

  • https://www.projectcbd.org/fibromyalgia

​

• Cannabis for treatment resitant fibromyalgia:

  • ​https://norml.org/news/2021/02/25/study-cannabis-mitigates-symptoms-in-patients-with-treatment-resistant-fibromyalgia

​

• CBD and fibromyalgia:

  • https://www.healthline.com/health/cbd-for-fibromyalgia

​

• Blog post on CBD and fibromyalgia:

  • https://fibromyalgianewstoday.com/2017/11/03/seeking-fibro-pain-relief-cbd-oil-my-experience/

​

• Fibromyalgia:

  • ​https://www.linkedin.com/pulse/cannabis-conditions-fibromyalgia-curt-robbins/

  •  https://pubmed.ncbi.nlm.nih.gov/33118602

​

• Ehlers-Danlos Syndrome:

  • ​https://www.linkedin.com/pulse/cannabis-ehlers-danlos-syndrome-curt-robbins/

​

Fitness

​

• Article on CBD and fitness:

  • https://www.leafscience.com/2018/01/29/cbd-fitness-can-help/

​

• Cannabis and exercise:

  • https://www.leafly.com/news/health/three-things-everyone-should-know-about-cannabis-and-exercise

​

Gastrointestinal - IBD/IBS

​

• Published research – Endocannabinoid system is involved in gut microbiome make up, gut motility, and inflammation – explains why cannabis is likely helpful for IBD:

  • http://online.liebertpub.com/doi/pdfplus/10.1089/can.2016.0001

  • https://www.karger.com/Article/Pdf/517425

​

• Endocannabinoids in the gut

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574910/

​

• Cannabis and Gastrointestinal and Liver Disorders:

  • ​​https://www.gastrojournal.org/article/S0016-5085(20)30563-1/fulltext

​

• CBD may help relieve irritable bowel syndrome:

  • ​https://www.hellomd.com/health-wellness/5c79c6e1eb14100009da226f/cbd-may-help-relieve-irritable-bowel-syndrome

  • https://www.medicalnewstoday.com/articles/cbd-for-ibs#summary

​

• Endocannabinoid Deficiency in Irritable Bowel Syndrome:

  • ​https://www.liebertpub.com/doi/pdfplus/10.1089/can.2016.0009

​

• The role of cannabis in inflammatory bowel disease:

  • ​https://academic.oup.com/ibdjournal/article/25/3/427/5144402

​

• Cannabidiol in inflammatory bowel disease:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/22815234

​

• Cannabis improves symptoms of Crohn's

  • ​https://www.eurekalert.org/pub_releases/2018-10/sh-cis101518.php

  • https://pubmed.ncbi.nlm.nih.gov/23648372/ 

​

• Research study – abstract only - In a small study, cannabis improved Crohn’s disease symptoms, but didn’t cause remission:

  • http://www.cghjournal.org/article/S1542-3565(13)00604-6/fulltext

​

• Research study – Relatively little research has been done, but for patients with IBD, cannabis seems to help with symptoms and can reduce reliance on steroids:

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193087/

​

• CBD may improve gastric reflux/GERD:

  • ​​https://cbdeducationonline.com/cbd-and-acid-reflux-disease/

​

• How CBD can reduce acid reflux:

  • ​https://www.hellomd.com/health-wellness/5d2d118d39436208dea69dcd/how-cbd-can-help-reduce-acid-reflux

​

• CBD can decrease intestinal hyperpermeability (leaky gut):

  • ​https://pubmed.ncbi.nlm.nih.gov/31054246/

​

• Cannabinoids for gastroparesis:

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970440/

  • https://pubmed.ncbi.nlm.nih.gov/30865015/

  • https://norml.org/news/2022/09/01/study-cannabis-mitigates-pain-in-patients-with-refractory-gastroparesis-is-associated-with-improvements-in-in-hospital-mortality 

  • https://norml.org/news/2021/04/01/study-gastroparesis-patients-who-use-cannabis-possess-better-hospitalization-outcomes

​

• Cannabis hyperemesis syndrome:

  • ​​https://www.analyticalcannabis.com/articles/understanding-cannabis-hyperemesis-syndrome-311560

​

• Cannabidiol restores intestinal barrier dysfunction...  may improve leaky gut?

  • ​https://www.ncbi.nlm.nih.gov/pubmed/29238589

​

Headache/Migraines

​

• Forbes article on cannabis and headaches:

  • https://www.forbes.com/sites/daviddisalvo/2017/06/29/marijuana-treats-migraine-pain-better-than-prescription-medication-study-finds/#562302c33700

  • https://www.forbes.com/sites/ajherrington/2021/02/17/study-finds-cbd-is-an-effective-treatment-for-migraine/

​

• Cannabis and CBD to treat migraines:

  • ​https://www.projectcbd.org/cannabis-therapy-headaches

​

• Can CBD oil treat a migraine:

  • ​https://www.verywellhealth.com/cbd-oil-for-migraines-4570929

​

• WebMD article on cannabis and headache/migraines:

  • ​https://www.webmd.com/migraines-headaches/under-counter-treatment-migraines#1

​

• Endocannabinoid deficiency and migraines:

  • ​​https://www.liebertpub.com/doi/pdfplus/10.1089/can.2016.0009

​

• Published research – summary of history of cannabis for headache. Conclusion – probably effective, need randomized controlled trials:

  •  http://online.liebertpub.com/doi/pdf/10.1089/can.2016.0033

​

• Medical cannabis decreases migraine frequency:​

  • https://www.leafly.com/news/health/how-cannabis-can-help-migraine

  • https://drive.google.com/drive/folders/1K3wcEJugkkQBnRIeqQmcFWVwJkSxu5w

  • ​https://accpjournals.onlinelibrary.wiley.com/doi/full/10.1002/phar.1673

  • https://drive.google.com/drive/folders/1K3wcEJugkkQBnRIeqQmcFWVwJkSxu5wa

​

• Topical CBD for migraines:

  • ​https://www.migrainekey.com/blog/topical-cbd-for-migraine-relief/#_edn7

​

• NIH review of research on cannabis and headaches:

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436334/

​

HIV

​

• Current research - Abstract from the Center for Medicinal Cannabis Research, UCal – San Diego. Testing cannabis for HIV neuropathic pain:

  • https://www.cmcr.ucsd.edu/index.php/2015-11-20-20-52-15/active-studies/87-henry

​

Huntington's Disease

​

• Cannabinoids and Huntington's Disease:

  • https://norml.org/news/2018/04/05/study-cannabinoid-therapy-improves-dystonia-in-hd-patients

​

Liver disease

​

• Cannabis decreases fatty liver disease:

  • https://norml.org/news/2021/02/25/study-cannabis-use-associated-with-reduced-fatty-liver-index-scores-in-patients-co-infected-with-hivhcv

 

Lung health

​

• Longitudinal Study -Cannabis smoke exposure not associated with impaired lung function: 

  • https://norml.org/news/2023/01/26/study-cannabis-smoke-exposure-not-associated-with-impaired-lung-function/

​

• Cannabis smoke with less risk of pulmonary complications compared to tobacco smoke:

  • https://www.atsjournals.org/doi/pdf/10.1513/annalsats.201212-127fr 

​

• CBD and COPD:

  • https://lunginstitute.com/blog/can-cbd-cure-my-lung-disease/ 

​

• The Effect of Phytocannabinoids on Airway Hyper-Responsiveness, Airway Inflammation, and Cough:

  • https://jpet.aspetjournals.org/content/353/1/169

​

Multiple sclerosis

​

• Published research – Cannabis effective at controlling spasticity in MS:

  • http://www.cmaj.ca/content/184/10/1143.long

​

• CBD as a potential treatment for MS:

  • https://www.ncbi.nlm.nih.gov/pubmed/27890794

​

• List of research studies on use of cannabinoids in treatment of MS:

  • ​https://www.projectcbd.org/multiple-sclerosis-ms

​

• Cannabis for MS:

  • ​https://www.analyticalcannabis.com/articles/medical-marijuana-for-multiple-sclerosis-what-does-the-research-say-311947

​

• Can CBD improve motility in people with MS?:

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874292/

​

• Using CBD to treat MS:

  • ​https://multiplesclerosis.net/living-with-ms/cbd-hemp-how-helped/

​

• CBD may be beneficial in MS:

  • ​https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/j.1476-5381.2011.01379.x

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712515/

​

Pain​

​

• The biology of cannabis versus opioids for pain relief:

  • https://www.leafly.com/news/science-tech/medical-marijuana-opioid-pain-relief-substitute

​

• How cannabis relieves different types of pain:

  • ​https://www.leafly.com/news/health/how-marijuana-relieves-different-types-of-pain

​

• CBD for pain management:

  • https://www.marijuanabreak.com/cbd-helps-with-pain-management/

  • https://www.practicalpainmanagement.com/patient/treatments/marijuana-cannabis/empowered-pain-patient-guide-cbd

​

• Topical CBD for chronic back pain:

  • ​https://norml.org/news/2020/11/12/case-reports-cbd-skin-cream-mitigates-chronic-back-pain

​

• CBD to treat sciatica and disk pain:

  • ​https://www.spine-health.com/treatment/alternative-care/understanding-cbd-cannabidiol-back-pain

​

• The Role of the endocannabinoid system in pain control:

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430692/

​

• Cannabinoids for difficult to manage pain:

  • ​​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503660/

​

• CBD for neuropathy in feet:

  • ​​https://www.marijuanabreak.com/cbd-for-neuropathy-in-feet-possible-new-treatment

​

• Published research – Pharmacology and history suggest cannabis is effective for pain treatment:

  • http://online.liebertpub.com/doi/pdfplus/10.1089/can.2017.0028

​

• Published research – survey of patients who have used both opioids and cannabis – cannabis works as well as opioids, without side effects:

  • http://online.liebertpub.com/doi/pdfplus/10.1089/can.2017.0012

​

• Published research – cannabis moderately effective at reducing pain, may reduce opioid dependence:

  •  http://online.liebertpub.com/doi/pdfplus/10.1089/can.2017.0017

​

• The analgesic potential of cannabinoids:

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728280/

​

• Published research – Cannabis effective for neuropathic pain – abstract only:

  •  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666747/

​

• Published research – Cannabis effective for diabetic neuropathy in small clinical trial:

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152762/

​

• Leafly article on a Minnesota state survey of medical cannabis users showing that the majority found it effective for pain:
  • https://www.leafly.com/news/health/study-minnesota-patients-say-medical-marijuana-reduces-pain

​​

• Cannabis and CBD to treat Bell's Palsy:

  • https://cannabis.net/blog/medical/cannabis-research-for-bells-palsy

​

• Cannabis and CBD to treat trigeminal neuralgia:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/15578967

  • http://face-facts.org/medical-marijuana-chronic-facial-pain/

  • https://cannabishealthnews.co.uk/2021/10/01/trigeminal-neuralgia-how-cannabis-can-help-with-the-excruciating-pain/

​

• Medical cannabis associated with decreased opioid use:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/27001005

​

• Rationale for cannabis-based interventions in the opioid overdose crisis:

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563007/

​

• Cannabis use tied to decrease in opioid use and improved quality of life:

  • ​https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187795

​

• Adding cannabinoids to opioid treatment increases effectiveneCan marijuana be the answer to pain?:

  • ​https://www.webmd.com/a-to-z-guides/news/20180420/can-marijuana-be-the-answer-for-pain

​

​

Parkinson’s Disease

​

• CBD and Parkinson's:

  • https://www.projectcbd.org/science/cannabis-pharmacology/cbd-and-parkinsons-disease

​

• Nutrition in Parkinson's:

  • ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945400/

​

• CBD and Parkinson's disease:

  • ​​https://www.civilized.life/articles/cbd-oil-for-parkinsons-disease/

​

• Effect of CBD in the treatment of Parkinson's:

  • ​https://www.ncbi.nlm.nih.gov/pubmed/25237116

​

• Medical cannabis and Parkinson's:

  • ​https://www.michaeljfox.org/news/fox-insight-survey-sheds-light-cannabis-use-and-parkinsons

  • https://pubmed.ncbi.nlm.nih.gov/27723182/

  • https://www.michaeljfox.org/foundation/news-detail.php?ask-the-md-medical-marijuana-and-parkinson-disease-a

​

• Published research – Some preclinical trials have shown cannabis helps with motor issues from Parkinson’s:

  • http://online.liebertpub.com/doi/pdfplus/10.1089/can.2017.0002

​​

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